Our research outputs are evidenced by over 160 peer-reviewed publications, reviews, and other published contributions in the international literature.
The full list of our primary research articles can be found here.
The full list of our review and book chapter publications can be found here.
Selected Articles:
Selective Deuteration and Tritiation of Pharmaceutically Relevant Sulfoximines. B. I. P. Smith, N. M. L. Knight, G. J. Knox, D. M. Lindsay, L. C. Paterson, J. Bergare, C. S. Elmore, R. A. Bragg, and W. J. Kerr, Angew. Chem. Int. Ed., 2025, 64, e202417179.
Collaborative GSK-University of Strathclyde doctoral research and training programmes: Transforming approaches to industry-academia engaement. L. C. Paterson, P. G. Humphreys, H. A. Kelly, and W. J. Kerr, Drug Discov. Today, 2024, 29, 104162.
Experimental and computational insights into the mechanism of the copper(i)-catalysed sulfonylative Suzuki–Miyaura reaction. C. G. J. Hall, H. F. Sneddon, P. Pogany, D. M. Lindsay, and W. J. Kerr, Chem. Sci., 2023, 14, 6738-6755.
Catalyst design in C–H activation: a case study in the use of binding free energies to rationalise intramolecular directing group selectivity in iridium catalysis. W. J. Kerr, G. J. Knox, M. Reid, and T. Tuttle, Chem. Sci., 2021, 12, 6747-6755.
A Sustainable and Scalable Multicomponent Continuous Flow Process to Access Fused Imidazoheterocycle Pharmacophores. B. J. M. Baker, W. J. Kerr, D. M. Lindsay, V. K. Patel, and D. L. Poole, Green Chemistry, 2021, 23, 280-287.
Structure-based Design of a Bromodomain and Extraterminal Domain (BET) Inhibitor Selective for the N-terminal Bromodomains that Retains an Anti-inflammatory and Anti-proliferative Phenotype. C. R. Wellaway, P. Bamborough, S. G. Bernard, C.-w. Chung, P. D. Craggs, L. Cutler, E. H. Demont, J. P. Evans, L. Gordon, B. Karamshi, A. J. Lewis, M. J. Lindon, D. J. Mitchell, I. Rioja, P. E. Soden, S. Taylor, R. J. Watson, R. Willis, J. M. Woolven, B. S. Wyspiańska, W. J. Kerr, and R. K. Prinjha, J. Med. Chem., 2020, 63, 9020-9044.
Profile of a Highly Selective Quaternized Pyrrolidine Betaine αvβ6 integrin inhibitor – (3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S and 1R,3R)-1-methyl-3-(2- (5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation. T. N. Barrett, J. A. Taylor, D. Barker, P. A. Procopiou, J. D. F. Thompson, J. Barrett, J. Le, S. M. Lynn, P. Pogany, C. Pratley, J. M. Pritchard, J. A. Roper, J. E. Rowedder, R. J. Slack, G. Vitulli, S. J. F. Macdonald, and W. J. Kerr, J. Med. Chem., 2019, 62, 7543-7556.
PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase is Inhibited by Covalent Binding. C. P. Tinworth, H. Lithgow, L. Dittus, Z. I. Bassi, S. E. Hughes, M. Muelbaier, H. Dai, I. E. D. Smith, W. J. Kerr, G. A. Burley, M. Bantscheff, and J. D. Harling. ACS Chem. Biol., 2019, 14, 342-347.
Iridium-catalyzed Csp3-H Activation for Mild and Selective Hydrogen Isotope Exchange. W. J. Kerr, R. J. Mudd, M. Reid, J. Atzrodt, and V. Derdau, ACS Catal., 2018, 8, 10895−10900.
Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences. J. Atzrodt, V. Derdau, W. J. Kerr, and M. Reid, Angew. Chem. Int. Ed., 2018, 57, 1758-1784.
C–H Functionalization for Hydrogen Isotope Exchange. J. Atzrodt, V. Derdau, W. J. Kerr, and M. Reid, Angew. Chem. Int. Ed., 2018, 57, 3022-3047.
A Practical and General Amidation Method from Isocyanates Enabled by Flow Technology. J. D. Williams, W. J. Kerr, S. G. Leach, and D. M. Lindsay, Angew. Chem. Int. Ed., 2018, 57, 12126-12130.
Total Synthesis 2-epi-a-cedren-3-one via a Cobalt-catalysed Pauson-Khand Reaction. W. J. Kerr, M. McLaughlin, L. C. Paterson, and C. M. Pearson, Tetrahedron, 2018, 74, 5062-5068.
Site-selective Deuteration of N-Heterocycles via Iridium-Catalyzed Hydrogen Isotope Exchange. W. J. Kerr, D. M. Lindsay, P. K. Owens, M. Reid, T. Tuttle, and S. Campos, ACS Catal., 2017, 7, 7182-7186.
Iridium-catalyzed Formyl-selective Deuteration of Aldehydes. W. J. Kerr, M. Reid, and T. Tuttle, Angew. Chem. Int. Ed., 2017, 56, 7808-7812.
Iridium-catalysed ortho-H/D and -H/T Exchange under Basic Conditions: C-H Activation of Unprotected Tetrazoles. W. J. Kerr, D. M. Lindsay, M. Reid, J. Atzrodt, V. Derdau, P. Rojahn, and R. Weck, Chem. Commun., 2016, 52, 6669-6672.
Iridium(I) NHC/Phosphine Catalysts for Mild and Chemoselective Hydrogenation Processes. W. J. Kerr, R. J. Mudd, and J. A. Brown, Chem. Eur. J., 2016, 22, 4738-4742.
Kerr Group Research 