Opportunities

We have funded, industry-linked, PhD studentships available for study commencing as soon as possible and up until October 2022.

Tuned Iridium Catalysts to Deliver an Array of Synthetic Efficiency and Selectivity

This project will specifically expand upon our iridium-based catalysts for application in a portfolio of important transformations in organic synthesis and of direct relevance to the pharmaceutical industry. More specifically, we are now primed to appreciably extend our iridium-catalysed methods for C-H activation, including for application in hydrogen isotope exchange, hydrogenation, and C-C, C-O, and C-N bond formation. The studentship is funded in collaboration with world-leading pharmaceutical company, GSK, for a duration of 3.5 years.

Applications are currently considered all year round.

New Metal-Catalysed Methods for C-H Activation Processes

This project will explore new methods for directed meta-C-H activation using new catalyst classes developed in our laboratory, which have grown from state-of-the-art ortho-C-H activation catalysis. These new methods will deliver complementary, flexible, and powerful methods to access a variety of pharmaceutically desired organic products and isotopically labelled late stage candidate-type molecules. As part of the overall programme of work, computationally-driven methods will be used to inform catalyst design and investigate reaction mechanism, in addition to directing the emerging reaction scope. This studentship is funded in collaboration with world-leading pharmaceutical company, GSK, for a duration of 4 years.

Applications are currently accepted all year round.

Pushing the Boundaries of Protein Degradation: The Development of Novel PROTAC Technology for CNS Penetration and Inhaled Delivery

This project will explore the area of protein degradation through the application of proteolysis targeting chimeras (PROTACs) for central nervous system (CNS) and lung targeted therapies. Structural and physicochemical properties of potential PROTAC molecules will be assessed through synthesis and computational design. This 4 year studentship is funded by Medical Research Scotland and is fully collaborative with Charles River Research Discovery Services, Saffron Waldon, Essex, UK.  It is expected that the location of the studentship research will be split approximately 50:50 between the Company and the University laboratories.

The deadline for applications for this studentship is Wednesday, 17th November, 2021 at 5 pm.

How to apply

For all available studentships, applicants must have, or expect to obtain, a strong MChem (or equivalent) degree as a requirement of the funding. Additionally, the position is well suited to students with significant experience in Synthetic Organic Chemistry obtained either through industrial placement or as part of an MChem/MSci research project. Please submit your application by e-mail to Dr Laura C. Paterson (laura.c.paterson@strath.ac.uk), which should include:

  • Cover letter, detailing your experience and motivation for PhD studies; 
  • CV with the details of two referees;
  • Full transcripts from your undergraduate degree and any additional higher degree studies; and
  • Other pertinent information (e.g., publications, awards, and other distinctions)

The successful applicants will join our extremely motivated and industrious research team, and will receive elevated levels of training in the areas of preparative chemistry, organometallic-based synthesis, reaction mechanism, computational methods, and the associated analytical/spectroscopic requirements. Industrial partners will also provide key training opportunities as aligned to the individual projects.

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